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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50259958
Substrate
n/a
Meas. Tech.
ChEMBL_548799 (CHEMBL1034290)
IC50
50000±n/a nM
Citation
 Asano, N; Kato, A; Miyauchi, M; Kizu, H; Kameda, Y; Watson, AA; Nash, RJ; Fleet, GW Nitrogen-containing furanose and pyranose analogues from Hyacinthus orientalis. J Nat Prod 61:625-8 (1998) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN
Type:
PROTEIN
Mol. Mass.:
54093.12
Organism:
Bos taurus
Description:
ChEMBL_335897
Residue:
468
Sequence:
MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAKFGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNPDSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNIRYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPDTYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCTSIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTTKVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50259958
Synonyms:
(2R,3S,4S,5S)-2-(2-hydroxyethyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol | 2,5-imino-2,5,6-trideoxy-D-gulo-heptitol | CHEMBL464569
Type:
Small organic molecule
Emp. Form.:
C7H15NO4
Mol. Mass.:
177.1983
SMILES:
OCC[C@H]1N[C@@H](CO)[C@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: