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Target
Adenosine receptor A3
Ligand
BDBM50273839
Substrate
n/a
Meas. Tech.
ChEMBL_538318 (CHEMBL1036752)
Ki
182±n/a nM
Citation
 Stefanachi, A; Nicolotti, O; Leonetti, F; Cellamare, S; Campagna, F; Loza, MI; Brea, JM; Mazza, F; Gavuzzo, E; Carotti, A 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships. Bioorg Med Chem 16:9780-9 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50273839
Synonyms:
7-hydroxy-6-phenyl-1,3-dipropyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione | CHEMBL516154
Type:
Small organic molecule
Emp. Form.:
C18H21N3O3
Mol. Mass.:
327.3776
SMILES:
CCCn1c2c(O)c([nH]c2c(=O)n(CCC)c1=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: