Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50285020
Substrate
n/a
Meas. Tech.
ChEBML_40038
IC50
250±n/a nM
Citation
 Lowe, JA; Drozda, SE; McLean, S; Bryce, DK; Crawford, RT; Zorn, S; Morrone, J; Appleton, TA; Lombardo, F A water soluble benzazepine cholecystokinin-B receptor antagonist Bioorg Med Chem Lett 5:1933-1936 (1995)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50285020
Synonyms:
CHEMBL292856 | N-tert-Butyl-2-((3R,5R)-5-isopropyl-8-methyl-2-oxo-3-{3-[3-(1H-tetrazol-5-yl)-phenyl]-ureido}-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetamide
Type:
Small organic molecule
Emp. Form.:
C28H36N8O3
Mol. Mass.:
532.6372
SMILES:
CC(C)[C@H]1C[C@@H](NC(=O)Nc2cccc(c2)-c2nnn[nH]2)C(=O)N(CC(=O)NC(C)(C)C)c2cc(C)ccc12
Structure:
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