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Target
Carboxypeptidase B
Ligand
BDBM50296414
Substrate
n/a
Meas. Tech.
ChEMBL_580786 (CHEMBL1059768)
Ki
3600±n/a nM
Citation
 Fernández, D; Avilés, FX; Vendrell, J A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases. Eur J Med Chem 44:3266-71 (2009) [PubMed]  Article 
Target
Name:
Carboxypeptidase B
Synonyms:
CPB
Type:
Enzyme
Mol. Mass.:
48382.46
Organism:
Helicoverpa zea (Corn earworm moth) (Heliothis zea)
Description:
Q3T905
Residue:
429
Sequence:
MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREGVVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGARRAGDLFRK
  
Inhibitor
Name:
BDBM50296414
Synonyms:
CHEMBL552336 | N-(3-chlorophenyl)-4-((5-(3-methoxybenzylthio)-1,3,4-oxadiazol-2-yl)methyl)thiazol-2-amine
Type:
Small organic molecule
Emp. Form.:
C20H17ClN4O2S2
Mol. Mass.:
444.958
SMILES:
COc1cccc(CSc2nnc(Cc3csc(Nc4cccc(Cl)c4)n3)o2)c1
Structure:
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