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Target
Cholecystokinin receptor type A
Ligand
BDBM50298578
Substrate
n/a
Meas. Tech.
ChEMBL_587760 (CHEMBL1040411)
IC50
17850±n/a nM
Citation
 Hadjipavlou-Litina, D; Braiuca, P; Lassiani, L; Pavan, MV; Varnavas, A 2D-QSAR and 3D-QSAR/CoMFA analyses of the N-terminal substituted anthranilic acid based CCK(1) receptor antagonists: 'Hic Rhodus, hic saltus'. Bioorg Med Chem 17:5198-206 (2009) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
Rat
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50298578
Synonyms:
(+/-)-2-(2-(3-(1H-indol-3-yl)propanamido)benzamido)-3-phenylpropanoic acid | CHEMBL573555
Type:
Small organic molecule
Emp. Form.:
C27H25N3O4
Mol. Mass.:
455.5051
SMILES:
OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)CCc1c[nH]c2ccccc12
Structure:
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