Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50302303
Substrate
n/a
Meas. Tech.
ChEMBL_596700 (CHEMBL1049670)
Ki
7±n/a nM
Citation
 Chu, GH; Saeui, CT; Worm, K; Weaver, DG; Goodman, AJ; Broadrup, RL; Cassel, JA; DeHaven, RN; LaBuda, CJ; Koblish, M; Brogdon, B; Smith, S; Le Bourdonnec, B; Dolle, RE Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists. Bioorg Med Chem Lett 19:5931-5 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Human
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50302303
Synonyms:
1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-yl)cyclohexanecarboxamide | CHEMBL567942
Type:
Small organic molecule
Emp. Form.:
C20H31N3O2
Mol. Mass.:
345.479
SMILES:
CCC1(CCCCC1)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1
Structure:
Search PDB for entries with ligand similarity: