Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50325576
Substrate
n/a
Meas. Tech.
ChEMBL_652250 (CHEMBL1225453)
Ki
44.9±n/a nM
Citation
 Lange, JH; Attali, A; van der Neut, MA; Wals, HC; Mulder, A; Zilaout, H; Duursma, A; van Aken, HH; van Vliet, BJ Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists. Bioorg Med Chem Lett 20:4992-8 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50325576
Synonyms:
3-butyl-4-(3-fluorophenyl)-N-(2-(4-fluorophenyl)propan-2-yl)-4,5-dihydro-1H-pyrazole-1-carboxamide | CHEMBL1223590
Type:
Small organic molecule
Emp. Form.:
C23H27F2N3O
Mol. Mass.:
399.4768
SMILES:
CCCCC1=NN(CC1c1cccc(F)c1)C(=O)NC(C)(C)c1ccc(F)cc1 |t:4|
Structure:
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