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Target
Low molecular weight protein-tyrosine phosphatase A
Ligand
BDBM50331859
Substrate
n/a
Meas. Tech.
ChEMBL_686940 (CHEMBL1291351)
Ki
36300±n/a nM
Citation
 Chandra, K; Dutta, D; Das, AK; Basak, A Design, synthesis and inhibition activity of novel cyclic peptides against protein tyrosine phosphatase A from Mycobacterium tuberculosis. Bioorg Med Chem 18:8365-73 (2010) [PubMed]  Article 
Target
Name:
Low molecular weight protein-tyrosine phosphatase A
Synonyms:
PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA
Type:
Hydrolase
Mol. Mass.:
17891.84
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
163
Sequence:
MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
  
Inhibitor
Name:
BDBM50331859
Synonyms:
4,9-Dioxo-3-(phenyl-phenylamino-methyl)-[1,5]diazonane-6-carboxylic acid | CHEMBL1289456
Type:
Small organic molecule
Emp. Form.:
C21H23N3O4
Mol. Mass.:
381.425
SMILES:
OC(=O)[C@H]1CCC(=O)NC[C@H]([C@@H](Nc2ccccc2)c2ccccc2)C(=O)N1 |r|
Structure:
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