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Target
ERO1-like protein alpha
Ligand
BDBM50336425
Substrate
n/a
Meas. Tech.
ChEMBL_716824 (CHEMBL1670746)
IC50
54000±n/a nM
Citation
 Chu, Y; Chen, X; Yang, Y; Tang, Y Identification of small molecular inhibitors for Ero1p by structure-based virtual screening. Bioorg Med Chem Lett 21:1118-21 (2011) [PubMed]  Article 
Target
Name:
ERO1-like protein alpha
Synonyms:
ERO1-L | ERO1-L-alpha | ERO1A | ERO1A_HUMAN | ERO1L | Endoplasmic oxidoreductin-1-like protein | Oxidoreductin-1-L-alpha
Type:
PROTEIN
Mol. Mass.:
54384.46
Organism:
Homo sapiens (Human)
Description:
ChEMBL_716824
Residue:
468
Sequence:
MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
  
Inhibitor
Name:
BDBM50336425
Synonyms:
2-methoxy-4-((2-(naphthalen-2-yl)-5-oxooxazol-4(5H)-ylidene)methyl)phenyl acetate | CHEMBL1668292
Type:
Small organic molecule
Emp. Form.:
C23H17NO5
Mol. Mass.:
387.3848
SMILES:
COc1cc(\C=C2\N=C(OC2=O)c2ccc3ccccc3c2)ccc1OC(C)=O |c:7|
Structure:
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