Reaction Details Report a problem with these data
Target
Transcriptional activator protein TraR
Ligand
BDBM50266198
Substrate
n/a
Meas. Tech.
ChEMBL_765233 (CHEMBL1827786)
IC50
460±n/a nM
Citation
 Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein TraR
Synonyms:
TRAR_RHIRD | traR
Type:
PROTEIN
Mol. Mass.:
26741.83
Organism:
Rhizobium radiobacter
Description:
ChEMBL_765233
Residue:
234
Sequence:
MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTYFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
  
Inhibitor
Name:
BDBM50266198
Synonyms:
(S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluoromethoxy)phenoxy)acetamide | CHEMBL503197
Type:
Small organic molecule
Emp. Form.:
C13H12F3NO5
Mol. Mass.:
319.2333
SMILES:
FC(F)(F)Oc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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