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Target
Cytochrome P450 2D6
Ligand
BDBM50355852
Substrate
n/a
Meas. Tech.
ChEMBL_775157 (CHEMBL1912462)
IC50
950±n/a nM
Citation
 Packiarajan, M; Coate, H; Desai, M; Jimenez, HN; Reinhard, EJ; Jubian, VJ; Marzabadi, MR; Chandrasena, G; Wolinski, TC; Walker, MW; Andersen, K 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. Bioorg Med Chem Lett 21:6500-4 (2011) [PubMed]  Article 
Target
Name:
Cytochrome P450 2D6
Synonyms:
CP2D6_HUMAN | CYP2D6 | CYP2DL1 | CYPIID6 | Cytochrome P450 2D6 (CYP2D6) | Debrisoquine 4-hydroxylase | P450-DB1
Type:
Protein
Mol. Mass.:
55774.82
Organism:
Homo sapiens (Human)
Description:
P10635
Residue:
497
Sequence:
MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR
  
Inhibitor
Name:
BDBM50355852
Synonyms:
CHEMBL1909725
Type:
Small organic molecule
Emp. Form.:
C15H23N5O2S2
Mol. Mass.:
369.505
SMILES:
CN(C)S(=O)(=O)NCCCCCNc1nc(cs1)-c1ccccn1
Structure:
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