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Target
P2Y purinoceptor 2
Ligand
BDBM50366154
Substrate
n/a
Meas. Tech.
ChEMBL_805630 (CHEMBL1960464)
EC50
400±n/a nM
Citation
 Van Poecke, S; Barrett, MO; Santhosh Kumar, T; Sinnaeve, D; Martins, JC; Jacobson, KA; Kendall Harden, T; Van Calenbergh, S Synthesis and P2Y2 receptor agonist activities of uridine 5'-phosphonate analogues. Bioorg Med Chem 20:2304-15 (2012) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50366154
Synonyms:
CHEMBL1957440
Type:
Small organic molecule
Emp. Form.:
C16H18FN2O8P
Mol. Mass.:
416.2949
SMILES:
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CCP(O)(O)=O)n1cc(-c2ccc(F)cc2)c(=O)[nH]c1=O |r|
Structure:
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