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Target
Platelet-activating factor receptor
Ligand
BDBM81972
Substrate
n/a
Meas. Tech.
ChEMBL_155143 (CHEMBL760184)
Ki
14.3±n/a nM
Citation
 Bugianesi, RL; Ponpipom, MM; Parsons, WH; Hwang, S; Doebber, TW; Lam, M; Wu, MS; Alberts, AW; Chabala, JC Synthesis and biological activity of the platelet-activating factor antagonist ()-trans-2-(3-methoxy-4-phenylsulfonylethoxy-5-n-propylsulfonylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (L-671,284) and its analogs Bioorg Med Chem Lett 2:181-184 (1992)    Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM81972
Synonyms:
(S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROBROMIDE | Alpha-Methylhistamine-S | CAS_75614-93-6
Type:
Small organic molecule
Emp. Form.:
C6H11N3
Mol. Mass.:
125.1716
SMILES:
C[C@H](N)Cc1cnc[nH]1 |r|
Structure:
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