Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50028653
Substrate
n/a
Meas. Tech.
ChEMBL_76213 (CHEMBL687941)
IC50
510±n/a nM
Citation
 Ramakrishnan, K; Portoghese, PS Synthesis and biological evaluation of a metazocine-containing enkephalinamide. Evidence for nonidentical roles of the tyramine moiety in opiates and opioid peptides. J Med Chem 25:1423-7 (1983) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50028653
Synonyms:
(+)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carbonitrile | (-)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carbonitrile | CHEMBL441776
Type:
Small organic molecule
Emp. Form.:
C16H20N2O
Mol. Mass.:
256.3428
SMILES:
CC1C2Cc3ccc(O)cc3C1(C)CC(C#N)N2C |THB:0:1:17.13.14:10.3.4|
Structure:
Search PDB for entries with ligand similarity: