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Target
Kappa-type opioid receptor
Ligand
BDBM50045117
Substrate
n/a
Meas. Tech.
ChEMBL_146377 (CHEMBL754734)
Ki
1116±n/a nM
Citation
 Ronsisvalle, G; Pasquinucci, L; Pappalardo, MS; Vittorio, F; Fronza, G; Romagnoli, C; Pistacchio, E; Spampinato, S; Ferri, S Non-peptide ligands for opioid receptors. Design of kappa-specific agonists. J Med Chem 36:1860-5 (1993) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Guinea pig
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50045117
Synonyms:
6,11-Dimethyl-3-(3-phenyl-propyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
Type:
Small organic molecule
Emp. Form.:
C23H29NO
Mol. Mass.:
335.4825
SMILES:
CC1C2Cc3ccc(O)cc3[C@]1(C)CCN2CCCc1ccccc1 |TLB:9:10:1:15.13.14,16:15:1:10.4.3|
Structure:
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