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Target
Kappa-type opioid receptor
Ligand
BDBM50045119
Substrate
n/a
Meas. Tech.
ChEMBL_146377 (CHEMBL754734)
Ki
>25000±n/a nM
Citation
 Ronsisvalle, G; Pasquinucci, L; Pappalardo, MS; Vittorio, F; Fronza, G; Romagnoli, C; Pistacchio, E; Spampinato, S; Ferri, S Non-peptide ligands for opioid receptors. Design of kappa-specific agonists. J Med Chem 36:1860-5 (1993) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Guinea pig
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50045119
Synonyms:
2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2,6-methano-benzo[d]azocin-3-ylmethyl)-1-phenyl-cyclopropanecarboxylic acid butyl ester | CHEMBL301066
Type:
Small organic molecule
Emp. Form.:
C29H37NO3
Mol. Mass.:
447.609
SMILES:
CCCCOC(=O)[C@@]1(CC1CN1CC[C@]2(C)[C@@H](C)[C@H]1Cc1ccc(O)cc21)c1ccccc1 |TLB:10:11:16:26.20.19|
Structure:
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