Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50029350
Substrate
n/a
Meas. Tech.
ChEMBL_63059 (CHEMBL673626)
Ki
2490±n/a nM
Citation
 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH (+/-)-(N-alkylamino)benzazepine analogs: novel dopamine D1 receptor antagonists. J Med Chem 38:4284-93 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50029350
Synonyms:
CHEMBL135834 | [4-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-butyl]-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C23H31BrN2O
Mol. Mass.:
431.409
SMILES:
COc1cc2C(CN(CCCCN(C)C)CCc2cc1Br)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: