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Target
Delta-type opioid receptor
Ligand
BDBM50050506
Substrate
n/a
Meas. Tech.
ChEMBL_53450 (CHEMBL666300)
IC50
118±n/a nM
Citation
 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity. J Med Chem 39:2081-6 (1996) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50050506
Synonyms:
(-) 3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-9-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate | 3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-9-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate | CHEMBL440123
Type:
Small organic molecule
Emp. Form.:
C22H24N2O2
Mol. Mass.:
348.4382
SMILES:
COc1ccc2c3c(CC4CC3(CCN4C)c3cccc(O)c3)[nH]c2c1
Structure:
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