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Target
Integrase
Ligand
BDBM50073629
Substrate
n/a
Meas. Tech.
ChEMBL_88621 (CHEMBL701725)
IC50
1070±n/a nM
Citation
 King, PJ; Ma, G; Miao, W; Jia, Q; McDougall, BR; Reinecke, MG; Cornell, C; Kuan, J; Kim, TR; Robinson, WE Structure-activity relationships: analogues of the dicaffeoylquinic and dicaffeoyltartaric acids as potent inhibitors of human immunodeficiency virus type 1 integrase and replication. J Med Chem 42:497-509 (1999) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50073629
Synonyms:
2,3-Bis-(2,3-dihydroxy-benzoyloxy)-succinic acid | CHEMBL357831
Type:
Small organic molecule
Emp. Form.:
C18H14O12
Mol. Mass.:
422.2966
SMILES:
OC(=O)C(OC(=O)c1cccc(O)c1O)C(OC(=O)c1cccc(O)c1O)C(O)=O
Structure:
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