Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50369512
Substrate
n/a
Meas. Tech.
ChEMBL_30488 (CHEMBL642102)
Ki
1.1±n/a nM
Citation
 van Tilburg, EW; von Frijtag Drabbe Künzel, J; de Groote, M; Vollinga, RC; Lorenzen, A; IJzerman, AP N6,5'-Disubstituted adenosine derivatives as partial agonists for the human adenosine A3 receptor. J Med Chem 42:1393-400 (1999) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Human
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50369512
Synonyms:
CHEMBL605054
Type:
Small organic molecule
Emp. Form.:
C19H21IN6O4
Mol. Mass.:
524.3123
SMILES:
CNC(=O)C[C@H]1OC([C@@H](O)[C@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12 |r|
Structure:
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