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Target
Methionine aminopeptidase 1
Ligand
BDBM50129642
Substrate
n/a
Meas. Tech.
ChEMBL_105134 (CHEMBL715018)
IC50
200±n/a nM
Citation
 Luo, QL; Li, JY; Liu, ZY; Chen, LL; Li, J; Qian, Z; Shen, Q; Li, Y; Lushington, GH; Ye, QZ; Nan, FJ Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae. J Med Chem 46:2631-40 (2003) [PubMed]  Article 
Target
Name:
Methionine aminopeptidase 1
Synonyms:
MAP 1 | MAP1 | MAP1_YEAST | MetAP 1 | Peptidase M 1
Type:
PROTEIN
Mol. Mass.:
43382.92
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_10701
Residue:
387
Sequence:
MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSPGGPRQRIK
  
Inhibitor
Name:
BDBM50129642
Synonyms:
CHEMBL86427 | Phenyl-acetic acid 2-(thiazol-2-ylcarbamoyl)-pyridin-3-yl ester
Type:
Small organic molecule
Emp. Form.:
C17H13N3O3S
Mol. Mass.:
339.368
SMILES:
O=C(Cc1ccccc1)Oc1cccnc1C(=O)Nc1nccs1
Structure:
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