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Target
D(1B) dopamine receptor
Ligand
BDBM50164604
Substrate
n/a
Meas. Tech.
ChEMBL_303388 (CHEMBL839015)
Ki
15000±n/a nM
Citation
 Di Stefano, A; Sozio, P; Cacciatore, I; Cocco, A; Giorgioni, G; Costa, B; Montali, M; Lucacchini, A; Martini, C; Spoto, G; Di Pietrantonio, F; Di Matteo, E; Pinnen, F Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists. J Med Chem 48:2646-54 (2005) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM50164604
Synonyms:
Allyl-((1R,2R)-6-fluoro-5-methoxy-1-phenyl-indan-2-yl)-methyl-amine; hydrochloride | CHEMBL535151
Type:
Small organic molecule
Emp. Form.:
C20H22FNO
Mol. Mass.:
311.3932
SMILES:
COc1cc2C[C@H]([C@@H](c2cc1F)c1ccccc1)N(C)CC=C
Structure:
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