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Target
Bcl-2-like protein 2
Ligand
BDBM50202274
Substrate
n/a
Meas. Tech.
ChEMBL_441639 (CHEMBL891870)
Ki
61900±n/a nM
Citation
 Xing, C; Wang, L; Tang, X; Sham, YY Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1. Bioorg Med Chem 15:2167-76 (2007) [PubMed]  Article 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM50202274
Synonyms:
2-[5-(diphenylmethylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylpentanoic acid | CHEMBL439400
Type:
Small organic molecule
Emp. Form.:
C22H21NO3S2
Mol. Mass.:
411.537
SMILES:
[#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-1-[#6](=S)-[#16]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6]-1=O)-[#6](-[#8])=O
Structure:
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