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Target
Mu-type opioid receptor
Ligand
BDBM50375377
Substrate
n/a
Meas. Tech.
ChEMBL_471597 (CHEMBL940228)
Ki
5700±n/a nM
Citation
 Jung, B; Englberger, W; Fröhlich, R; Schepmann, D; Lehmkuhl, K; Wünsch, B Synthesis and pharmacological evaluation of bicyclic SNC80 analogues with separated benzhydryl moiety. Bioorg Med Chem 16:2870-85 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50375377
Synonyms:
CHEMBL409266
Type:
Small organic molecule
Emp. Form.:
C28H39N3O
Mol. Mass.:
433.6288
SMILES:
CCCN1C[C@@H]2[C@@H](CC[C@H]1CN2Cc1ccc(cc1)C(=O)N(CC)CC)c1ccccc1 |TLB:2:3:10.11:8.7.6,THB:26:6:3.4:10.11,12:11:3.4:8.7.6|
Structure:
Search PDB for entries with ligand similarity: