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Target
Mu-type opioid receptor
Ligand
BDBM50375380
Substrate
n/a
Meas. Tech.
ChEMBL_471597 (CHEMBL940228)
Ki
6320±n/a nM
Citation
 Jung, B; Englberger, W; Fröhlich, R; Schepmann, D; Lehmkuhl, K; Wünsch, B Synthesis and pharmacological evaluation of bicyclic SNC80 analogues with separated benzhydryl moiety. Bioorg Med Chem 16:2870-85 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50375380
Synonyms:
CHEMBL407728
Type:
Small organic molecule
Emp. Form.:
C28H37N3O
Mol. Mass.:
431.6129
SMILES:
CCN(CC)C(=O)c1ccc(CN2C[C@@H]3CC[C@@H]([C@H]2CN3CC=C)c2ccccc2)cc1 |TLB:24:17:20.19:13.12,11:12:20.19:15.16.17,THB:21:20:13.12:15.16.17|
Structure:
Search PDB for entries with ligand similarity: