Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50375623
Substrate
n/a
Meas. Tech.
ChEMBL_473539 (CHEMBL939093)
Ki
>1000±n/a nM
Citation
 Tabrizi, MA; Baraldi, PG; Preti, D; Romagnoli, R; Saponaro, G; Baraldi, S; Moorman, AR; Zaid, AN; Varani, K; Borea, PA 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists. Bioorg Med Chem 16:2419-30 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50375623
Synonyms:
CHEMBL259177
Type:
Small organic molecule
Emp. Form.:
C23H26BrN7O3
Mol. Mass.:
528.402
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cc(C)n(CC(=O)Nc2ccc(Br)cc2)n1
Structure:
Search PDB for entries with ligand similarity: