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Target
Somatostatin receptor type 2
Ligand
BDBM50261384
Substrate
n/a
Meas. Tech.
ChEMBL_532736 (CHEMBL972310)
IC50
337±n/a nM
Citation
 Grace, CR; Erchegyi, J; Samant, M; Cescato, R; Piccand, V; Riek, R; Reubi, JC; Rivier, JE Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity. J Med Chem 51:2676-81 (2008) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50261384
Synonyms:
CHEMBL526550 | H-DPhe2-c[Ncy3-Phe7-DTrp8-Lys9-Thr10-Ncy14]-Thr15-NH2
Type:
Small organic molecule
Emp. Form.:
C47H61N11O10S2
Mol. Mass.:
1004.185
SMILES:
C[C@@H](O)[C@H](NC(=O)[C@@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccccc2)SS1)[C@@H](C)O)C(N)=O |r|
Structure:
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