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Target
Vasopressin V2 receptor
Ligand
BDBM50307120
Substrate
n/a
Meas. Tech.
ChEMBL_609622 (CHEMBL1065237)
Ki
6.4±n/a nM
Citation
 Frantz, MC; Rodrigo, J; Boudier, L; Durroux, T; Mouillac, B; Hibert, M Subtlety of the structure-affinity and structure-efficacy relationships around a nonpeptide oxytocin receptor agonist. J Med Chem 53:1546-62 (2010) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
40295.28
Organism:
Homo sapiens (Human)
Description:
P30518
Residue:
371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
  
Inhibitor
Name:
BDBM50307120
Synonyms:
5-[4-[(1,1'-Biphenyl-2-ylcarbonyl)amino]-3-methylbenzoyl]-1-methyl-1,4,5,10-tetrahydropyrazolo[3,4-b][1,5]benzodiazepine | CHEMBL602872
Type:
Small organic molecule
Emp. Form.:
C32H27N5O2
Mol. Mass.:
513.5891
SMILES:
Cc1cc(ccc1NC(=O)c1ccccc1-c1ccccc1)C(=O)N1Cc2cnn(C)c2Nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: