Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50321587
Substrate
n/a
Meas. Tech.
ChEMBL_639731 (CHEMBL1175620)
Ki
640±n/a nM
Citation
 Thalji, RK; Aiyar, N; Davenport, EA; Erhardt, JA; Kallal, LA; Morrow, DM; Senadhi, S; Burns-Kurtis, CL; Marino, JP Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists. Bioorg Med Chem Lett 20:4104-7 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50321587
Synonyms:
1-(4-butoxyphenyl)-3-(2-(2-isopropylphenyl)benzofuran-7-yl)urea | CHEMBL1170327
Type:
Small organic molecule
Emp. Form.:
C28H30N2O3
Mol. Mass.:
442.5494
SMILES:
CCCCOc1ccc(NC(=O)Nc2cccc3cc(oc23)-c2ccccc2C(C)C)cc1
Structure:
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