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Target
MBT domain-containing protein 1
Ligand
BDBM50330500
Substrate
n/a
Meas. Tech.
ChEMBL_684951 (CHEMBL1286366)
IC50
>100000±n/a nM
Citation
 Kireev, D; Wigle, TJ; Norris-Drouin, J; Herold, JM; Janzen, WP; Frye, SV Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds. J Med Chem 53:7625-31 (2010) [PubMed]  Article 
Target
Name:
MBT domain-containing protein 1
Synonyms:
MBT domain-containing protein 1 | MBT domain-containing protein 1 (MBTD1) | MBTD1 | MBTD1_HUMAN
Type:
Protein
Mol. Mass.:
70557.67
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
628
Sequence:
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQESNGSANFYIKQEP
  
Inhibitor
Name:
BDBM50330500
Synonyms:
4-(4-chloro-3-ethylphenoxy)-N-methylbutan-1-amine | CHEMBL1275706
Type:
Small organic molecule
Emp. Form.:
C13H20ClNO
Mol. Mass.:
241.757
SMILES:
CCc1cc(OCCCCNC)ccc1Cl
Structure:
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