Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 5
Ligand
BDBM50389587
Substrate
n/a
Meas. Tech.
ChEMBL_832750 (CHEMBL2067846)
IC50
9200±n/a nM
Citation
 Zhang, F; Arnatt, CK; Haney, KM; Fang, HC; Bajacan, JE; Richardson, AC; Ware, JL; Zhang, Y Structure activity relationship studies of natural product chemokine receptor CCR5 antagonist anibamine toward the development of novel anti prostate cancer agents. Eur J Med Chem 55:395-408 (2012) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 5
Synonyms:
C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor
Type:
Enzyme
Mol. Mass.:
40540.21
Organism:
Homo sapiens (Human)
Description:
P51681
Residue:
352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
  
Inhibitor
Name:
BDBM50389587
Synonyms:
CHEMBL2064265
Type:
Small organic molecule
Emp. Form.:
C20H32N
Mol. Mass.:
286.4742
SMILES:
CCCCCCCC\C=C\c1c2CCC[n+]2c(C)cc1C
Structure:
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