Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 1
Ligand
BDBM50390980
Substrate
n/a
Meas. Tech.
ChEMBL_836339 (CHEMBL2076503)
Ki
19000±n/a nM
Citation
 Chen, R; Nelson, JA Role of organic cation transporters in the renal secretion of nucleosides. Biochem Pharmacol 60:215-9 (2000) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
Adrenaline alpha1 | Oct1 | Organic cation transporter 1 | S22A1_RAT | Slc22a1 | Solute carrier family 22 member 1 | adrenergic Alpha1 | rOCT1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
61538.40
Organism:
Rat
Description:
Adrenaline alpha1 0 RAT::Q63089
Residue:
556
Sequence:
MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLGPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLLMIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQVQTGKSSST
  
Inhibitor
Name:
BDBM50390980
Synonyms:
CHEMBL2074595
Type:
Small organic molecule
Emp. Form.:
C11H14N4O3
Mol. Mass.:
250.2539
SMILES:
Nc1ncnc2n(ccc12)[C@H]1C[C@H](O)[C@@H](CO)O1 |r|
Structure:
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