Reaction Details Report a problem with these data
Target
Urotensin-2 receptor
Ligand
BDBM50413016
Substrate
n/a
Meas. Tech.
ChEMBL_496756 (CHEMBL1005393)
Ki
1000±n/a nM
Citation
 Wang, Y; Wu, Z; Guida, BF; Lawrence, SK; Neeb, MJ; Rivero, RA; Douglas, SA; Jin, J N-alkyl-5H-pyrido[4,3-b]indol-1-amines and derivatives as novel urotensin-II receptor antagonists. Bioorg Med Chem Lett 18:4936-9 (2008) [PubMed]  Article 
Target
Name:
Urotensin-2 receptor
Synonyms:
Urotensin II receptor
Type:
PROTEIN
Mol. Mass.:
41170.15
Organism:
Cat
Description:
ChEMBL_496756
Residue:
374
Sequence:
MALSPAPLSGFPEPSAAPNASLNRSWASPTEPSSLEDLVATGAIGAVLSAMGVVGVAGNAYTLVVMCRVLHTSASMSVYVVNLALADLLYLLSIPFIVATYVTKEWHFGDVGCRVLFSLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRSKGYRKVLALGTWLLALLLALPMMLAIRLVHRGHKSLCLPVWGPRAHRAYLTLLFGTSIVGPGTVIGLLYVRLARAYWLSQRASFTQTRRLPNPKVLYLILGIVLLFWACFLPFWLWQLLAQYRGAQTLTPRTARIVNYLTTCLTYGNSCVNPFLYTLLTKNYREYRRRSLRARSARGPAGARHSLPCRVRFQRGSGHSLCSSSQQATETITLSPAASRAVCA
  
Inhibitor
Name:
BDBM50413016
Synonyms:
CHEMBL496516
Type:
Small organic molecule
Emp. Form.:
C16H13N3S
Mol. Mass.:
279.36
SMILES:
C(Nc1nccc2[nH]c3ccccc3c12)c1cccs1
Structure:
Search PDB for entries with ligand similarity: