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Target
G-protein coupled receptor 39
Ligand
BDBM50443619
Substrate
n/a
Meas. Tech.
ChEMBL_1279426 (CHEMBL3096582)
EC50
3100±n/a nM
Citation
 Boehm, M; Hepworth, D; Loria, PM; Norquay, LD; Filipski, KJ; Chin, JE; Cameron, KO; Brenner, M; Bonnette, P; Cabral, S; Conn, E; Ebner, DC; Gautreau, D; Hadcock, J; Lee, EC; Mathiowetz, AM; Morin, M; Rogers, L; Smith, A; VanVolkenburg, M; Carpino, PA Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example. ACS Med Chem Lett 4:1079-84 (2013) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 39
Synonyms:
GPR39 | GPR39_HUMAN
Type:
PROTEIN
Mol. Mass.:
51351.94
Organism:
Human
Description:
ChEMBL_107977
Residue:
453
Sequence:
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
  
Inhibitor
Name:
BDBM50443619
Synonyms:
CHEMBL3092412
Type:
Small organic molecule
Emp. Form.:
C28H33N3O2
Mol. Mass.:
443.5805
SMILES:
COc1cccc(c1)[C@@H]1CCN(CCc2ccccc2)C[C@H]1C(=O)NCCc1ccccn1 |r|
Structure:
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