Reaction Details Report a problem with these data
Target
Carboxylic ester hydrolase
Ligand
BDBM50016874
Substrate
n/a
Meas. Tech.
ChEMBL_1355058 (CHEMBL3280472)
Ki
1500±n/a nM
Citation
 Chen, WS; Cocolas, GH; Cavallito, CJ; Chai, KJ Potent reversible anticholinesterase agents. Bis- and mono-N-substituted benzoquinolinium halides. J Med Chem 20:1617-23 (1978) [PubMed]  Article 
Target
Name:
Carboxylic ester hydrolase
Synonyms:
BuChE | Butyrlcholinesterase (BuChE) | Butyrylcholine esterase | Butyrylcholinesterase | Butyrylcholinesterase (BChE) | Butyrylcholinesterase (BuChE) | Butyrylcholinesterase (EqBuChE) | Carboxylic ester hydrolase | butyrylcholinesterase precursor
Type:
Protein
Mol. Mass.:
68842.83
Organism:
Horse
Description:
Q9N1N9
Residue:
602
Sequence:
MQSWGTIICIRILLRFLLLWVLIGNSHTEEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTKKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEILSRSIMKRWANFAKYGNPNGTQSNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF
  
Inhibitor
Name:
BDBM50016874
Synonyms:
CHEMBL3276409
Type:
Small organic molecule
Emp. Form.:
C36H46Br2N2
Mol. Mass.:
666.572
SMILES:
[Br-].[Br-].C[N+](C)(CCCCCC[N+](C)(C)Cc1ccc(cc1)-c1ccccc1)Cc1ccc(cc1)-c1ccccc1
Structure:
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