Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM50013792
Substrate
n/a
Meas. Tech.
ChEMBL_1543853 (CHEMBL3749743)
Ki
8.2±n/a nM
Citation
 Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett 26:401-5 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
4.2.1.1 | Carbonate dehydratase
Type:
PROTEIN
Mol. Mass.:
28438.71
Organism:
Sulfurihydrogenibium sp. (strain YO3AOP1)
Description:
ChEMBL_116696
Residue:
246
Sequence:
MRKILISAVLVLSSISISFAEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINIDKKYKVKANLPKLNLYYKTAKESEVVNNGHTIQINIKEDNTLNYLGEKYQLKQFHFHTPSEHTIEKKSYPLEIHFVHKTEDGKILVVGVMAKLGKTNKELDKILNVAPAEEGEKILDKNLNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNNRPVQEINSRWIIEGF
  
Inhibitor
Name:
BDBM50013792
Synonyms:
CHEBI:6822 | METHAZOLAMIDE | Neptazane
Type:
Small organic molecule
Emp. Form.:
C5H8N4O3S2
Mol. Mass.:
236.272
SMILES:
CC(=O)\N=c1\sc(nn1C)S(N)(=O)=O
Structure:
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