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Target
Histamine H3 receptor
Ligand
BDBM50220109
Substrate
n/a
Meas. Tech.
ChEBML_87054
Ki
3.6±n/a nM
Citation
 Faghih, R; Dwight, W; Gentles, R; Phelan, K; Esbenshade, TA; Ireland, L; Miller, TR; Kang, CH; Fox, GB; Gopalakrishnan, SM; Hancock, AA; Bennani, YL Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1. Bioorg Med Chem Lett 12:2031-4 (2002) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50220109
Synonyms:
CHEMBL304714
Type:
Small organic molecule
Emp. Form.:
C20H30N2O4
Mol. Mass.:
362.4632
SMILES:
CCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)OCC)cc1
Structure:
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