Reaction Details
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5-hydroxytryptamine receptor 1A
Ligand
BDBM82564
Substrate
n/a
Ki
1.9±n/a nM
Comments
PDSP_1655
Citation
Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | HTR1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45800.53
Organism:
pigeon
Description:
5-HT1A HTR1A pigeon::A0A1V4KRM0
Residue:
413
Sequence:
MDVANNTTSPERSPEGAGGPGLAEVTLGYQLLTSLLLGTLILCAVSGNACVIAAIALERSLQTVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDIFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAVLISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFKAARFRIRKTVRKVEKKKVADTCLTLSPSALQKKSNGEPGKGWRRTVEHKPGVCVNGAVRQGEDGAALEIIEVQRCNSSSKTHLPLPSEACGSPPPPSFEKRNEKNTEAKRRMALSRERKTVKTLGIIMGTFILCWLPFFIVALVLPFCDSKCYMPKWLEAVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCKFCRQ
Inhibitor
Name:
BDBM82564
Synonyms:
CAS_132787 | NSC_132787 | S 15535
Type:
Small organic molecule
Emp. Form.:
C21H24N2O2
Mol. Mass.:
336.4275
SMILES:
C1C(Cc2ccccc12)N1CCN(CC1)c1cccc2OCCOc12
Structure:
