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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM85338
Substrate
n/a
Ki
82±n/a nM
Comments
PDSP_782
Citation
 Abramovitz, M; Adam, M; Boie, Y; Carrière, M; Denis, D; Godbout, C; Lamontagne, S; Rochette, C; Sawyer, N; Tremblay, NM; Belley, M; Gallant, M; Dufresne, C; Gareau, Y; Ruel, R; Juteau, H; Labelle, M; Ouimet, N; Metters, KM The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483:285-93 (2000) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM85338
Synonyms:
CAS_73121-56-9 | ENPROSTIL | NSC_5282207
Type:
Small organic molecule
Emp. Form.:
C23H28O6
Mol. Mass.:
400.4648
SMILES:
COC(=O)CCC=C=CCC1C(C=CC(O)COc2ccccc2)C(O)CC1=O |w:12.11,(-.79,-17.87,;.54,-17.1,;1.88,-17.87,;1.88,-19.41,;3.21,-17.1,;4.55,-17.87,;5.88,-17.1,;7.21,-17.87,;8.55,-18.64,;9.88,-17.87,;11.21,-18.64,;12.62,-18.02,;12.94,-16.51,;14.41,-16.03,;14.73,-14.53,;13.58,-13.5,;16.19,-14.05,;16.51,-12.55,;17.98,-12.07,;18.3,-10.56,;19.76,-10.09,;20.9,-11.12,;20.58,-12.62,;19.12,-13.1,;13.65,-19.16,;15.18,-19,;12.88,-20.49,;11.38,-20.17,;10.23,-21.2,)|
Structure:
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