Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM93025
Substrate
n/a
Meas. Tech.
Competition Binding Assay
Ki
2.3±0.6 nM
Citation
 Renault, N; Laurent, X; Farce, A; El Bakali, J; Mansouri, R; Gervois, P; Millet, R; Desreumaux, P; Furman, C; Chavatte, P Virtual Screening of CB2 Receptor Agonists from Bayesian Network and High-Throughput Docking: Structural Insights into Agonist-Modulated GPCR Features. Chem Biol Drug Des 81:442-454 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Human
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM93025
Synonyms:
CB2 Inhibitor, 1
Type:
Small molecule
Emp. Form.:
C25H35NO2
Mol. Mass.:
381.5509
SMILES:
CCCCCC(C)C(C)c1cc(O)c2C3=C(CCN(C3)C#C)C(C)(C)Oc2c1 |t:14|
Structure:
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