Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50186430
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
7.2±n/a
Temperature
298.15±n/a K
IC50
5000±n/a nM
Comments
extracted
Citation
 Al-Abed, Y Modified macrophage migration inhibitory factor inhibitors US Patent  US8618147 Publication Date 12/31/2013 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
MIF_MOUSE | Macrophage migration inhibitory factor (MIF) | Mif
Type:
Enzyme
Mol. Mass.:
12505.65
Organism:
Mus musculus (Mouse)
Description:
P34884
Residue:
115
Sequence:
MPMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA
  
Inhibitor
Name:
BDBM50186430
Synonyms:
CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
Type:
Small organic molecule
Emp. Form.:
C18H23NO4
Mol. Mass.:
317.3795
SMILES:
Oc1ccc(cc1)C1=NOC(CC(=O)OCC2CCCCC2)C1 |t:8|
Structure:
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