Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM135795
Substrate
n/a
Meas. Tech.
Binding Inhibition Assay
pH
7.5±n/a
Temperature
298.15±n/a K
Ki
1.8±n/a nM
Comments
extracted
Citation
 Kinoyama, I; Miyazaki, T; Koganemaru, Y; Washio, T; Hamaguchi, W Nitrogenous-ring acylguanidine derivative US Patent  US8853242 Publication Date 10/7/2014 
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme
Mol. Mass.:
40266.25
Organism:
Human
Description:
P47898
Residue:
357
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
  
Inhibitor
Name:
BDBM135795
Synonyms:
US8853242, 192
Type:
Small organic molecule
Emp. Form.:
C18H15FN4O
Mol. Mass.:
322.3363
SMILES:
[#6]-c1cnc(-c2ccccc2F)c2cc(ccc12)-[#6](=O)\[#7]=[#6](\[#7])-[#7]
Structure:
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