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Target
D(3) dopamine receptor
Ligand
BDBM141829
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
2.14±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzofurane-piperidine compounds US Patent  US8921397 Publication Date 12/30/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM141829
Synonyms:
US8921397, 71
Type:
Small organic molecule
Emp. Form.:
C32H42N2O3
Mol. Mass.:
502.6875
SMILES:
CC(C)(C)Oc1ccc(cc1)C(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 |r,wU:17.18,wD:14.14,(10.15,-.77,;11.49,0,;12.82,.77,;12.26,-1.33,;10.72,1.33,;9.18,1.33,;8.41,,;6.87,,;6.1,1.33,;6.87,2.67,;8.41,2.67,;4.56,1.33,;3.79,2.67,;3.79,,;2.25,,;1.48,1.33,;-.06,1.33,;-.83,,;-2.37,,;-3.14,-1.33,;-4.68,-1.33,;-5.45,,;-6.99,,;-7.76,-1.33,;-6.99,-2.67,;-5.45,-2.67,;-9.3,-1.33,;-10.21,-2.58,;-11.67,-2.1,;-11.67,-.56,;-12.82,.47,;-12.5,1.97,;-11.03,2.45,;-9.89,1.42,;-10.21,-.09,;-.06,-1.33,;1.48,-1.33,)|
Structure:
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