Reaction Details
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Serine/threonine-protein kinase Chk1 [2-280]
Ligand
BDBM225375
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
0.299±n/a nM
More Info.:
Target
Name:
Serine/threonine-protein kinase Chk1 [2-280]
Synonyms:
CHEK1 | CHK1 | CHK1_HUMAN | CHK1_Kinase
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Human
Description:
O14757[2-280]
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
Inhibitor
Name:
BDBM225375
Synonyms:
Chk1_144
Type:
Small Organic Molecule
Emp. Form.:
C23H19N3O3
Mol. Mass.:
385.4153
SMILES:
COc1cc2Cc3c(n[nH]c3-c3ccc(nc3)-c3ccc(O)cc3)-c2cc1OC
Structure:
