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Target
D(2) dopamine receptor
Ligand
BDBM50387560
Substrate
n/a
Meas. Tech.
Reception Binding Assay
Temperature
303.15±n/a K
Ki
223.61±n/a nM
IC50
1155.3±n/a nM
Comments
extracted
Citation
 Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Hexahydrodibenzo[a,g]quinolizine compound, preparation method thereof, pharmaceutical composition and use thereof US Patent  US9359372 Publication Date 6/7/2016 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50387560
Synonyms:
CHEMBL2057451 | US9359372, DC037017
Type:
Small organic molecule
Emp. Form.:
C21H25NO2
Mol. Mass.:
323.4287
SMILES:
COc1cc2CCN3Cc4c(C)cc(C)cc4C[C@H]3c2cc1OC |r|
Structure:
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