Reaction Details
Report a problem with these data
![](/images/Email.png)
Target
Proto-oncogene tyrosine-protein kinase Src [145-252]
Ligand
BDBM14674
Substrate
Peptide Substrate
Meas. Tech.
Scintillation Proximity Assay (SPA)
pH
7.4±n/a
Temperature
295.15±n/a K
IC50
>40000000±n/a nM
Citation
![](/images/small/blackdot.gif)
More Info.:
Target
Name:
Proto-oncogene tyrosine-protein kinase Src [145-252]
Synonyms:
Proto-oncogene tyrosine-protein kinase Src | Proto-oncogene tyrosine-protein kinase Src (aa 145-252) | SRC | SRC1 | SRC_HUMAN | c-Src pp60c-src | p60-Src
Type:
SH2 Domain
Mol. Mass.:
12362.36
Organism:
Homo sapiens (Human)
Description:
Src-SH2 proteins (amino acid residues 145-252) were chemically biotinylated using a 10-fold molar excess of D-biotin-N-hydroxy-succinimidester and purified by gel filtration yielding conjugates with an average ratio of two biotin moieties per protein molecule.
Residue:
108
Sequence:
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSK
Inhibitor
Name:
BDBM14674
Synonyms:
Fragment 4 | Oxalic Acid
Type:
Small organic molecule
Emp. Form.:
C2H2O4
Mol. Mass.:
90.0349
SMILES:
OC(=O)C(O)=O
Substrate
Name:
Peptide Substrate
Synonyms:
n/a
Type:
Peptide
Mol. Mass.:
1600.79
Organism:
n/a
Description:
Peptide EPQpYEEIPIYL (middle-T antigen) was monoiodinated on tyrosine.
Residue:
13
Sequence:
IEPQPYEEIPIYL