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Target
Sentrin-specific protease 8
Ligand
BDBM76793
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
4200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76793
Synonyms:
5-nitro-2-thiophenecarboxylic acid [2-(benzoylhydrazo)-2-oxoethyl] ester | 5-nitrothiophene-2-carboxylic acid [2-(N'-benzoylhydrazino)-2-keto-ethyl] ester | MLS002251387 | SMR001313791 | [2-(2-benzoylhydrazinyl)-2-oxoethyl] 5-nitrothiophene-2-carboxylate | [2-oxidanylidene-2-[2-(phenylcarbonyl)hydrazinyl]ethyl] 5-nitrothiophene-2-carboxylate | cid_2612220
Type:
Small organic molecule
Emp. Form.:
C14H11N3O6S
Mol. Mass.:
349.319
SMILES:
[O-][N+](=O)c1ccc(s1)C(=O)OCC(=O)NNC(=O)c1ccccc1
Structure:
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