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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM53484
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
9832±750 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM53484
Synonyms:
6-Benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium | MLS001207496 | N-[(E)-2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-2-benzimidazol-3-iumyl]ethenyl]-N-methylaniline;iodide | N-[(E)-2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-benzimidazol-3-ium-2-yl]ethenyl]-N-methyl-aniline;iodide | N-[(E)-2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenylbenzimidazol-3-ium-2-yl]ethenyl]-N-methylaniline;iodide | O-acyl oxime isatin derivative, 63 | SMR000504738 | [(E)-2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-benzimidazol-3-ium-2-yl]vinyl]-methyl-phenyl-amine;iodide | cid_5719375
Type:
Small organic molecule
Emp. Form.:
C31H27N4S
Mol. Mass.:
487.637
SMILES:
CC[n+]1c(\C=C\N(C)c2ccccc2)n(-c2ccccc2)c2ccc(cc12)-c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: