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Target
C-C chemokine receptor type 6
Ligand
BDBM50895
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
>66600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM50895
Synonyms:
(4Z)-4-[[5-(2,5-dichlorophenyl)-2-furanyl]methylidene]-3-methyl-5-isoxazolone | (4Z)-4-[[5-(2,5-dichlorophenyl)-2-furyl]methylene]-3-methyl-2-isoxazolin-5-one | (4Z)-4-[[5-(2,5-dichlorophenyl)furan-2-yl]methylidene]-3-methyl-1,2-oxazol-5-one | (4Z)-4-[[5-[2,5-bis(chloranyl)phenyl]furan-2-yl]methylidene]-3-methyl-1,2-oxazol-5-one | 4-{[5-(2,5-dichlorophenyl)-2-furyl]methylene}-3-methyl-5(4H)-isoxazolone | MLS000534352 | SMR000141784 | cid_5733602
Type:
Small organic molecule
Emp. Form.:
C15H9Cl2NO3
Mol. Mass.:
322.143
SMILES:
CC1=NOC(=O)\C1=C/c1ccc(o1)-c1cc(Cl)ccc1Cl |t:1|
Structure:
Search PDB for entries with ligand similarity: