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Target
Cysteine protease ATG4B
Ligand
BDBM80934
Substrate
n/a
Meas. Tech.
Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B.
IC50
11900±n/a nM
Citation
 PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay (2011)[AID] 
Target
Name:
Cysteine protease ATG4B
Synonyms:
APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44279.79
Organism:
Homo sapiens (Human)
Description:
gi_47132611
Residue:
393
Sequence:
MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
  
Inhibitor
Name:
BDBM80934
Synonyms:
(2,6-dichlorobenzyl)-(4-pyrrolidinophenyl)amine | (2,6-dichlorobenzyl)[4-(1-pyrrolidinyl)phenyl]amine | MLS000662049 | N-[(2,6-dichlorophenyl)methyl]-4-(1-pyrrolidinyl)aniline | N-[(2,6-dichlorophenyl)methyl]-4-pyrrolidin-1-ylaniline | N-[[2,6-bis(chloranyl)phenyl]methyl]-4-pyrrolidin-1-yl-aniline | SMR000292692 | cid_893102
Type:
Small organic molecule
Emp. Form.:
C17H18Cl2N2
Mol. Mass.:
321.244
SMILES:
Clc1cccc(Cl)c1CNc1ccc(cc1)N1CCCC1
Structure:
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